Caspase 4 anticorps (AA 91-105)

N° du produit ABIN1886902

Cet anticorps Lapin Polyclonal détecte spécifiquement Caspase 4 dans WB, IHC et ELISA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour Caspase 4 anticorps (AA 91-105) (ABIN1886902)

Antigène: Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caspase 4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-Caspase 4 anticorps

Épitope: AA 91-105

Purification: Ion exchange chromatography purified

Immunogène: Peptide corresponding to amino acids 91 to 105 of human caspase-13.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur Caspase 4

Antigène: Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))

Autre désignation: Caspase-13

Sujet: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands.Cell death is finally caused by members of the caspase family of proteases and caspase activated DNases.A novel member in the caspase family was recently identified and designated ERICE (for Evolutionarily Related Interleukin-1 beta Converting Enzyme) and caspase-13.Caspase-13 belongs to the ICE subfamily of caspases.Overexpression of caspase-13 induces apoptosis.Caspase-13 was activated by caspase-8, which is a key enzyme in death receptor induced apoptosis.Caspase-13 is expressed in a variety of human tissues and cell lines.
Synonyms: Casp-13, ERICE

Poids moléculaire: 43 kDa

UniProt: O75601

Pathways: Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity